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Master of Science in Nursing Program: Evidence-Based Practice

EBP Resources

Evidence Hierarchies refer to the ranking of research studies based on the strength and reliability of their findings. In evidence-based nursing and healthcare, higher levels of evidence come from studies that minimize bias and provide stronger support for clinical decision-making.

A simplified hierarchy (from strongest to weakest evidence) is:

  1. Systematic Reviews & Meta-Analyses – Combine results from multiple high-quality studies (often RCTs) to give the most reliable conclusions.

  2. Randomized Controlled Trials (RCTs) – Participants are randomly assigned to intervention or control groups; considered the gold standard for testing interventions.

  3. Cohort Studies – Follow groups over time to examine relationships between exposures and outcomes.

  4. Case-Control Studies – Compare people with a condition to those without to find possible causes or risk factors.

  5. Cross-Sectional & Descriptive Studies – Provide a snapshot of a population or phenomenon at one point in time.

  6. Qualitative Studies – Explore experiences, perceptions, or processes to understand why and how phenomena occur.

  7. Expert Opinion / Background Information – Based on clinical expertise or non-research sources; valuable but least strong in terms of scientific evidence.

For more information:

PICO in Evidence Based Practice

By Carrie Price | Towson University Library

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